THC is the compound in the cannabis plant responsible for its psychoactive effect. Because THC makes you “high”, it’s often regarded as a harmful component of the Cannabis sativa plant, but this perception is not an objective one, as THC has its positive effects as well. The other powerful component in cannabis, CBD, was also proven to reduce inflammation and is thought to play a role in the treatment of arthritis symptoms. Of all the compounds in the Cannabis sativa plant, the ones that play a role in inhibiting inflammation are the substances that activate the CB2 receptors. The CB2 receptors are part of the endocannabinoid system along with CB1 receptors, the first ones being found in the central nervous system and influencing perception, memory, mood, sleep and appetite, while CB2 receptors are involved in immunity. Cannabidiol (CBD) is not the only compound in cannabis that activates the CB2 receptor. Another substance called beta-carophyllene also activates this receptor, and has no psychoactive effect. Combining CBD with natural, well known plants like tea tree oil, turmeric, ginger, holy basil, aloe vera and cinnamon can make for a powerful anti-inflammatory combination.